Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
LS7000000
CHEMICAL NAME :
Fructopyranose,
beta-D-
CAS REGISTRY NUMBER :
7660-25-5
BEILSTEIN REFERENCE NO.
:
1423189
LAST UPDATED :
199706
DATA ITEMS CITED :
7
MOLECULAR FORMULA
:
C6-H12-O6
MOLECULAR WEIGHT :
180.18
WISWESSER LINE NOTATION :
T6OTJ BQ B1Q
CQ DQ EQ FRUCTO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 -
Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED
:
Rodent - rat
DOSE/DURATION :
12600 mg/kg
TOXIC EFFECTS :
Details of toxic
effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan
(Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year:
-,254,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE
:
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>20
gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose
value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd.,
Tokyo, Japan) Volume(issue)/page/year: -,254,1990
TYPE OF TEST :
LD50 - Lethal dose,
50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent -
rat
DOSE/DURATION :
12750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not
reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical
Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,254,1990
TYPE
OF TEST :
LD30 - Lethal Dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES
OBSERVED :
Rodent - mouse
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of
toxic effects not reported other than lethal dose value
REFERENCE :
AGACBH Agents and
Actions, A Swiss Journal of Pharmacology. (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
Switzerland) V.1- 1969/70- Volume(issue)/page/year: 16,580,1985
TYPE OF TEST :
LD50 -
Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED
:
Rodent - mouse
DOSE/DURATION :
9400 mg/kg
TOXIC EFFECTS :
Details of toxic
effects not reported other than lethal dose value
REFERENCE :
ARZNAD
Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960
Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,72,1958
TYPE OF TEST
:
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES
OBSERVED :
Rodent - rabbit
DOSE/DURATION :
13350 mg/kg
TOXIC EFFECTS
:
Details of toxic effects not reported other than lethal dose value
REFERENCE
:
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan)
Volume(issue)/page/year: -,254,1990 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo -
Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED
:
Rodent - mouse
DOSE/DURATION :
5000 mg/kg
TOXIC EFFECTS :
Tumorigenic -
equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of
application
REFERENCE :
GANNA2 Gann. Japanese Journal of Cancer Research. (Tokyo,
Japan) V.1-75, 1907-84. For publisher information, see JJCREP. Volume(issue)/page/year:
46,371,1955
