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sorbic acid
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Basic
Common Name Sorbic acid
CAS Number 110-44-1
Molecular Weight 112.127
Density 1.0±0.1 g/cm3
Boiling Point 233.0±9.0 °C at 760 mmHg
Molecular Formula C6H8O2
Melting Point 132-135 °C(lit.)
MSDS Chinese USA
Flash Point 139.9±9.6 °C
Symbol GHS07
Signal Word Warning
Physical Chemistry
Density 1.0±0.1 g/cm3
Boiling Point 233.0±9.0 °C at 760 mmHg
Melting Point 132-135 °C(lit.)
Molecular Formula C6H8O2
Molecular Weight 112.127
Flash Point 139.9±9.6 °C
Exact Mass 112.052429
PSA 37.30000
LogP 1.35
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.488
Stability Stability Material saturated with this acid may ignite spontaneously. Incompatible with strong oxidizing agents. May be light sensitive.
Water Solubility 1.6 g/L (20 ºC)
Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
WG2100000
CHEMICAL NAME :
Sorbic acid
CAS REGISTRY NUMBER :
110-44-1
LAST UPDATED :
199701
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C6-H8-O2
MOLECULAR WEIGHT :
112.14
WISWESSER LINE NOTATION :
QV1U2U2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Human - man
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7360 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2820 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2820 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1040 mg/kg/65W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
MUTATION DATA
TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
1050 mg/L
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 22,501,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81510 No. of Facilities: 583 (estimated) No. of Industries: 6 No. of Occupations: 11 No. of Employees: 4662 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81510 No. of Facilities: 4412 (estimated) No. of Industries: 45 No. of Occupations: 59 No. of Employees: 69243 (estimated) No. of Female Employees: 21637 (estimated)
Safety
Symbol GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/38
Safety Phrases S26-S36-S24/25
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS WG2100000
HS Code 2916190090
Preparation

N/A

FAQ

1.What is the history of Sorbic Acid?

A.W. von Hofmann discovered sorbic acid in 1859 by the distillation of rowanberry oil. This results in parasorbic acid, the lactone of sorbic acid, which he hydrolyzed to produce sorbic acid. The late 1930s and early 1940s saw the discovery of its antibacterial properties, and the late 1940s and early 1950s saw its commercial availability. Sorbic acid and its salts have been used as Clostridium botulinum inhibitors in meat products since the 1980s, replacing the usage of nitrites, which can result in carcinogenic nitrosamines.

2.How is Sorbic Acid produced?

It is commercially synthesized from the condensation between ketene and crotonaldehyde instead of extracted from berries. The manufacturing process is described in the first three steps of production of potassium sorbate.

3.Is sorbic acid safe?

After reviewing their safety, the FDA declared that sorbic acid and potassium sorbate were generally recognized as safe food preservatives that could be added directly to food. Sorbic acid and potassium sorbate are used to effectively manage mold and yeast in the production of: cheese,baked goods,fruit juices,fresh fruits and vegetables,wines,soft drinks,pickles,sauerkraut, and some fish and meat items. The Cosmetic Ingredient Review (CIR) Expert Panel has reviewed the safety of sorbic acid and potassium sorbate. After analyzing the available scientific evidence, the CIR Expert Panel concluded that sorbic acid and potassium sorbate were safe to use in cosmetic and personal care products.

4.What is Sorbic Acid used for?

Three uses of sorbic acid include: 1.Food industry: Antimicrobial compounds such as sorbic acid and its salts, particularly potassium sorbate and calcium sorbate, are frequently used as preservatives in food to stop the growth of mold, yeast, and fungi. Sorbic acid has the benefit of not fading over time and is very powerful against fungus. In the presence of ethanol and sulfur, a fungistatic dosage is typically 200 mg/L. Generally speaking, salts are chosen over acids because they are more soluble in water, yet acid is the form that is actually active. A pH level under 6.5 is ideal for antibacterial action. Usually, doses of 0.025 to 0.10 percent are used for sorbates. However, adding sorbate salts can slightly alter the pH of the food, so the pH may need to be changed to ensure safety. Mineral deposits can be eliminated using sorbic acid. Although sorbic acid has subtle sensory qualities on its own, some people find it particularly repulsive. It is present in a variety of foods, including: Margarine,Sauces,Soups,Dried meats,Sausages,Nuggets,Bread,Muffins,Donuts,Pies,Cookies,Protein bars,Tacos,Pizzas,Smoked fish. 2.Wine industry: Off-dry wines are frequently treated with sorbic acid to stop fermentation in the bottle. It is typically used to inhibit Saccharomyces, and it does this reasonably well. This has the disadvantage that lactic acid bacteria, notably Oenococcus, can esterify it into alcohol (sorbyl alcohol), and this alcohol subsequently frequently rearranges and becomes 2-ethoxyhexa-3,5-diene, which has a disagreeable smell. Its sensory threshold has been estimated to be in the range of 100 ng/L, which is a negligibly low level. It has not been established that other genes in lactic acid bacteria can metabolize sorbic acid. To reduce the possibility of this off-odor in sweet reserves and when blended back the solids in wines should be removed, they should be filtered, adequately sulfited, and maintained at a low temperature. 3.Cosmetics: By killing germs, halting or delaying their growth and reproduction, sorbic acid and potassium sorbate guard against spoiling in cosmetics and personal care products.Cosmetics: By killing germs, halting or delaying their growth and reproduction, sorbic acid and potassium sorbate guard against spoiling in cosmetics and personal care products.

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