Common Name	Sodium propionate
CAS Number	137-40-6
Molecular Weight	96.060
Density	N/A
Boiling Point	141.7ºC at 760mmHg
Molecular Formula	C3H5NaO2
Melting Point	285-286 °C(lit.)
MSDS	Chinese USA
Flash Point	57.7ºC
Symbol	GHS07
Signal Word	Warning

Boiling Point	141.7ºC at 760mmHg
Melting Point	285-286 °C(lit.)
Molecular Formula	C3H5NaO2
Molecular Weight	96.060
Flash Point	57.7ºC
Exact Mass	96.018723
PSA	40.13000
Vapour Pressure	4.23mmHg at 25°C
Stability	Stable. Incompatible with strong oxidizing agents. Hygroscopic.
Water Solubility	995 g/L (20 ºC)

CHEMICAL IDENTIFICATION
RTECS NUMBER :
UF7525000
CHEMICAL NAME :
Propionic acid, sodium salt
CAS REGISTRY NUMBER :
137-40-6
LAST UPDATED :
199701
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C3-H5-O2.Na
MOLECULAR WEIGHT :
96.07
WISWESSER LINE NOTATION :
QV2 &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
8150 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 35(3),96,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6332 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NEZAAQ Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. (Nippon Eisei Gakkai, c/o Kyoto Daigaku Igakubu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.1- 1946- Volume(issue)/page/year: 28,463,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7800 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 35(3),96,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1640 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,60,1949
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
6750 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 35(3),96,1970 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
24817 mg/kg/9W-I
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - other changes
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 35(3),96,1970 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 69375 No. of Facilities: 349 (estimated) No. of Industries: 10 No. of Occupations: 12 No. of Employees: 3448 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 69375 No. of Facilities: 1499 (estimated) No. of Industries: 19 No. of Occupations: 32 No. of Employees: 29865 (estimated) No. of Female Employees: 14849 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H312
Precautionary Statements	P280
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R21;R38
Safety Phrases	S36/37-S36/37/39-S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	UF7525000
HS Code	2915509000

N/A

1.What is Sodium Propionate?

Sodium propionate (C3H5NaO2) is the sodium salt of propionic acid and is available as a white, free-flowing powder. In the food industry it is used safely as a food preservative and prevents the growth of mold and some bacteria. In pharmacy, it is used in the treatment of skin fungal infections, usually in combination with calcium propionate

2.How is Sodium Propionate produced?

Sodium propionate can be produced by the reaction of propionic acid (E280) with sodium hydroxide in hydrogen peroxide and water.

3.Is Sodium Propionate Safe to Eat?

Yes, it has been approved as a safe ingredient by the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA), as well as Joint FAO/WHO Expert Committee on Food Additives (JECFA).

4.What is Sodium Propionate used for?

Sodium propanoate is primarily used in baked goods to extend the shelf life and can also be used in the following foods in to inhibit the growth of mold and other microbes : Nonalcoholic beverages,Cheeses,Confections and frostings,Gelatins, puddings, and fillings,Jams and jellies,Meat products,Soft candy.The common use of sodium propionate is in bread and the recommended usage is 0.2-0.5% of flour weight for standard bakery recipes.