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propyl paraben
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Basic
Common Name Propyl paraben
CAS Number 94-13-3
Molecular Weight 180.201
Density 1.1±0.1 g/cm3
Boiling Point 294.3±13.0 °C at 760 mmHg
Molecular Formula C10H12O3
Melting Point 95-98 °C(lit.)
MSDS Chinese USA
Flash Point 124.6±12.6 °C
Physical Chemistry
Density 1.1±0.1 g/cm3
Boiling Point 294.3±13.0 °C at 760 mmHg
Melting Point 95-98 °C(lit.)
Molecular Formula C10H12O3
Molecular Weight 180.201
Flash Point 124.6±12.6 °C
Exact Mass 180.078644
PSA 46.53000
LogP 2.93
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.532
Stability Stable. Incompatible with strong oxidizing agents, strong bases.
Water Solubility
Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
DH2800000
CHEMICAL NAME :
Benzoic acid, p-hydroxy-, propyl ester
CAS REGISTRY NUMBER :
94-13-3
BEILSTEIN REFERENCE NO. :
1103245
LAST UPDATED :
199701
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C10-H12-O3
MOLECULAR WEIGHT :
180.22
WISWESSER LINE NOTATION :
QR DVO3
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6332 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NEZAAQ Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. (Nippon Eisei Gakkai, c/o Kyoto Daigaku Igakubu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.1- 1946- Volume(issue)/page/year: 28,463,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1650 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 128,135,1960
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
6 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 146,208,1929 *** REVIEWS *** TOXICOLOGY REVIEW ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,575,1954 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80496 No. of Facilities: 2827 (estimated) No. of Industries: 21 No. of Occupations: 36 No. of Employees: 48242 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80496 No. of Facilities: 13566 (estimated) No. of Industries: 86 No. of Occupations: 117 No. of Employees: 526606 (estimated) No. of Female Employees: 355310 (estimated)
Safety
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S24/25
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS DH2800000
HS Code 2918290000
Preparation

N/A

FAQ

1.What is Propyl Paraben?

Propylparaben is a preservative used in skincare and cosmetic formulations. Propylparaben is classed as a paraben, a group of preservatives with slightly different functions and anti-microbial activity based on their size. Other common parabens include methylparaben, butylparaben, isobutylparaben, and ethylparaben. If you’re researching mica, you might be looking for clean yet effective skincare. One brand we recommend is Carrot & Stick. You can read more about this brand at the bottom of the article. Propylparaben is used to extend the shelf-life of a product life by preventing microbial contamination. Microbial contamination can occur from exposure to bacteria and molds in the air and general use of the product from your hands. Preservatives like parabens are designed to reduce the likelihood that bacteria and molds can grow in your product. This is important for ensuring the safety of a product.

2.Why Is Propylparaben Used?

Propylparaben functions as a preservative in cosmetics and personal care products. In most formulations, parabens are used at very low levels ranging from 0.01 to 0.3%. The use of preservatives is necessary to prevent microbial contamination, as well as to prevent degradation by environmental factors such as heat, light, and air.

3.What are Benefits of Propylparabens?

The function of any type of parabens, propylparabens included, speaks more toward the end formulation of the product versus any type of direct benefit for the skin. "Any product that contains water is susceptible to being spoiled by the growth of fungi or bacteria, which could cause problems such as discoloration, malodor, or breakdown of the product," says Clark. "Under certain conditions, an inadequately preserved product can become contaminated, allowing harmful microorganisms to grow." And while you don't want to be using a cosmetic product that's riddled with bacteria for obvious reasons (aka the yuck factor), decreasing the risk of microbial contamination is also important because that contamination could potentially lead to skin irritation or even infection, points out King.

4.How Do You Use Parabens Safely?

The typical concentration of parabens used in cosmetics is 0.01 to 0.3 percent. Due to the controversy around parabens, they are highly regulated both in Europe and the United States. Their use is limited to low concentrations. There is little reason to be concerned about their use. However, if you are using a large number of paraben-containing products, then you may be exposing your skin to higher-than-normal levels of the ingredient. This may slightly increase the risk of irritation. If you have sensitive skin it may be useful to become familiar with common preservatives in order to reduce this risk.

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