Common Name	Ferrous gluconate
CAS Number	299-29-6
Molecular Weight	464.155
Density	N/A
Boiling Point	N/A
Molecular Formula	C12H24FeO15
Melting Point	N/A
MSDS	N/A
Flash Point	N/A

Molecular Formula	C12H24FeO15
Molecular Weight	464.155
Exact Mass	464.046448
PSA	264.13000
Stability	May be light-sensitive - store in the dark.

CHEMICAL IDENTIFICATION
RTECS NUMBER :
LZ5150000
CAS REGISTRY NUMBER :
299-29-6
LAST UPDATED :
199701
DATA ITEMS CITED :
17
MOLECULAR FORMULA :
C12-H22-Fe-O14
MOLECULAR WEIGHT :
446.19
WISWESSER LINE NOTATION :
Q1YQYQYQYQVO & 2-FE-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - child
DOSE/DURATION :
162 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting
REFERENCE :
JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year: 218,1179,1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2237 mg/kg
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: UR-3490-168
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3950 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AJMSA9 American Journal of the Medical Sciences. (Slack Inc., 6900 Grove Rd., Thorofare, NJ 08086) New series: V.1- 1841- Volume(issue)/page/year: 241,296,1961
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AJMSA9 American Journal of the Medical Sciences. (Slack Inc., 6900 Grove Rd., Thorofare, NJ 08086) New series: V.1- 1841- Volume(issue)/page/year: 241,296,1961
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
199 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AJMSA9 American Journal of the Medical Sciences. (Slack Inc., 6900 Grove Rd., Thorofare, NJ 08086) New series: V.1- 1841- Volume(issue)/page/year: 241,296,1961 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2600 mg/kg/13W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - lymphoma, including Hodgkin's disease Reproductive - Tumorigenic effects - ovarian tumors
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 24,109,1960 *** REVIEWS *** TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 4,615,1971 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1 mg(Fe)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,138,1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-DENMARK:TWA 1 mg(Fe)/m3 JAN 1993 OEL-FINLAND:TWA 1 mg(Fe)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 1 mg(Fe)/m3 JAN 1993 OEL-SWITZERLAND:TWA 1 mg(Fe)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 1 mg(Fe)/m3;STEL 2 mg(Fe)/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80415 No. of Facilities: 181 (estimated) No. of Industries: 2 No. of Occupations: 12 No. of Employees: 14676 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80415 No. of Facilities: 454 (estimated) No. of Industries: 4 No. of Occupations: 18 No. of Employees: 10496 (estimated) No. of Female Employees: 3906 (estimated)

Risk Phrases	22-24/25
Safety Phrases	S22-S24/25
WGK Germany	2
RTECS	LZ5150000
HS Code	2918160000

N/A

1.What is Ferrous Gluconate?

Ferrous gluconate or iron (II) gluconate, with iron in the +2 oxidation state, can be used as an iron supplement in food, a color additive for ripe olives, also for the treatment of iron deficiency anemia in medical uses. The European food additive number for it is E579.

2.How is Ferrous gluconate made?

It can be produced by the reaction of calcium gluconate, sulfuric acid, sodium carbonate and ferrous sulfate. And the following are the brief manufacturing process (1): 1.Obtain a gluconic acid solution: sulfuric acid reacts with calcium gluconate. 2.Obtain ferrous carbonate: the reaction between sodium carbonate and ferrous sulfate. 3.Gluconic acid solution reacts with excess ferrous carbonate. Ferrous gluconate can also be made from directly reacting gluconic acid (obtained from calcium gluconate) with iron powder.

3.Is Ferrous gluconate Safe to Eat?

Yes, it has been approved safe by the U.S. Food and Drug Administration (FDA) and European Food Safety Authority (EFSA), as well as the Joint FAO/WHO Expert Committee on Food Additives (JECFA).

4.What is Ferrous gluconate used for?

Ferrous gluconate is often used as an iron source for food fortification and in the treatment of anemia (blood is shorts of healthy red blood cells caused by insufficient iron) in medical uses. Let’s see the details. Food The uses of ferrous gluconate in food including as a nutrient supplement, such as in vitamins and minerals supplement, also in infant formula. It also can be used as a food coloring, making ripe olives black. Pharmaceutical Ferrous gluconate is used for treating or preventing iron deficiency anemia. Besides its pure form (powder or granular) sold as a bulk ingredient in the market, you can commonly find the tablet formulation of ferrous gluconate as an iron supplement with various dosages available in B2C market, for example, 324 mg, 325 mg, 300mg, 240 mg, 225 mg and so on. Iron quantities in them are around 38mg, 38mg, 35mg, 26mg, 28mg, respectively. Iron quantities are calculated by [the quantity of ferrous gluconate] multiply [the molecular weight of iron]divide [the molecular weight of ferrous gluconate]. In tablet formulations, the following ingredients may be included:Microcrystalline Cellulose，Methylcellulose，Titanium Dioxide，Silicon Dioxide，Triacetin，Magnesium Stearate，Polydextrose It can also be added in the production of multivitamin capsules and syrups. Regarding how much should take for anemia or max dose per day, possible side effects and other information, please visit Drugs.