Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
DH2200000
CHEMICAL NAME :
Benzoic acid,
p-hydroxy-, ethyl ester, sodium deriv.
CAS REGISTRY NUMBER :
35285-68-8
LAST
UPDATED :
199107
DATA ITEMS CITED :
2
MOLECULAR FORMULA
:
C9-H9-O3.Na
MOLECULAR WEIGHT :
188.17
WISWESSER LINE NOTATION :
OR DVO2
&-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose,
50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent -
mouse
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not
reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American
Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For
publisher information, see JPMSAE. Volume(issue)/page/year: 45,260,1956
TYPE OF TEST
:
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE
:
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
520
mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without
anesthesia (usually neuromuscular blockage) Behavioral - somnolence (general depressed
activity) Behavioral - ataxia
REFERENCE :
JAPMA8 Journal of the American
Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For
publisher information, see JPMSAE. Volume(issue)/page/year: 45,260,1956