Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
KN8970000
CHEMICAL NAME :
Ether,
diphenyl
CAS REGISTRY NUMBER :
101-84-8
BEILSTEIN REFERENCE NO.
:
1364620
LAST UPDATED :
199712
DATA ITEMS CITED :
33
MOLECULAR FORMULA
:
C12-H10-O
MOLECULAR WEIGHT :
170.22
WISWESSER LINE NOTATION :
ROR
HEALTH
HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
Standard Draize test
ROUTE OF
EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rat
REFERENCE
:
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St.,
Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 33,78,1975
TYPE OF TEST
:
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES
OBSERVED :
Rodent - rabbit
REFERENCE :
FCTXAV Food and Cosmetics Toxicology.
(London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7.
Volume(issue)/page/year: 12,707,1974
TYPE OF TEST :
Standard Draize test
ROUTE OF
EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent -
rabbit
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc.,
1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 33,78,1975 ** ACUTE
TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF
EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2450
mg/kg
TOXIC EFFECTS :
Behavioral - food intake (animal) Behavioral - muscle weakness
Gastrointestinal - other changes
REFERENCE :
NTIS** National Technical Information
Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical
Information. Volume(issue)/page/year: 0TS0518143
TYPE OF TEST :
LD50 - Lethal dose, 50
percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED
:
Rodent - rabbit
DOSE/DURATION :
>7940 mg/kg
REFERENCE :
NTIS** National
Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for
Scientific & Technical Information. Volume(issue)/page/year: 0TS0518143 *** REVIEWS ***
ACGIH TLV-STEL 14 mg/m3 (2 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological
Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA
7 mg/m3 (1 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH),
Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND
REGULATIONS *** MSHA STANDARD-air:TWA 1 ppm (7 mg/m3) (vapor) DTLVS* The Threshold Limit
Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference
of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
3,205,1971 OSHA PEL (Gen Indu):8H TWA 1 ppm (7 mg/m3), vapor CFRGBR Code of Federal
Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 1 ppm (7 mg/m3), vapor
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents,
Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 1
ppm (7 mg/m3), vapor CFRGBR Code of Federal Regulations. (U.S. Government Printing Office,
Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA
PEL (Fed Cont):8H TWA 1 ppm (7 mg/m3), vapor CFRGBR Code of Federal Regulations. (U.S.
Government Printing Office, Supt. of Documents, Washington, DC 20402)
Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRALIA:TWA 1 ppm (7 mg/m3);STEL 2 ppm (14 mg/m3) JAN 1993 OEL-AUSTRIA:TWA 1 ppm (7
mg/m3) JAN 1993 OEL-BELGIUM:TWA 1 ppm (7 mg/m3);STEL 2 ppm (14 mg/m3) JAN 1993
OEL-DENMARK:TWA 1 ppm (7 mg/m3) JAN 1993 OEL-FINLAND:TWA 1 ppm (7 mg/m3);STEL 3 ppm (21
mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 1 ppm (7 mg/m3) JAN 1993 OEL-GERMANY:TWA 1 ppm (7 mg/m3)
JAN 1993 OEL-HUNGARY:TWA 5 mg/m3;STEL 10 mg/m3;Skin JAN 1993 OEL-THE PHILIPPINES:TWA 1 ppm
(7 mg/m3) JAN 1993 OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 OEL-SWITZERLAND:TWA 1 ppm (7 mg/m3) JAN
1993 OEL-UNITED KINGDOM:TWA 1 ppm (7 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN,
KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH
STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO PHENYL ETHER, vapor-air:10H TWA 1 ppm REFERENCE : NIOSH* National Institute for
Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and
Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY
DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 57210 No. of
Facilities: 561 (estimated) No. of Industries: 17 No. of Occupations: 33 No. of Employees:
13791 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code -
57210 No. of Facilities: 7313 (estimated) No. of Industries: 62 No. of Occupations: 70 No.
of Employees: 90789 (estimated) No. of Female Employees: 33945 (estimated)
