Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
YK4570000
CHEMICAL NAME :
Triphosphoric
acid, pentasodium salt
CAS REGISTRY NUMBER :
7758-29-4
LAST UPDATED
:
199712
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
O10-P3.5Na
MOLECULAR
WEIGHT :
367.86
WISWESSER LINE NOTATION :
NA5 P3-O5
HEALTH HAZARD DATA
ACUTE
TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE
:
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3120 mg/kg
TOXIC
EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral -
coma
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA
22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0545589
TYPE OF TEST :
LD50 - Lethal dose, 50 percent
kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent -
rat
DOSE/DURATION :
525 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE
:
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co.,
428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year:
108,117,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE
:
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2060
mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose
value
REFERENCE :
VLUBB6 Vestnik Leningradskogo Universiteta, Biologiya. Journal of
Leningrad University, Biology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1956-
Volume(issue)/page/year: (3),97,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent
kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION
:
3100 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis
without anesthesia (usually neuromuscular blockage) Behavioral - somnolence (general
depressed activity) Behavioral - convulsions or effect on seizure threshold
REFERENCE
:
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya
Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 38(9),19,1973
TYPE OF
TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE
:
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
700
mg/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute
renal failure, acute tubular necrosis)
REFERENCE :
REPMBN Revue d'Epidemiologie,
Medecine Sociale et Sante Publique. (Masson Editeur, 120 Blvd. Saint-Germain, F-75280 Paris
Cedex O6, France) V.1- 1953- Volume(issue)/page/year: 10,391,1962
TYPE OF TEST :
LD50
- Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED
:
Rodent - mouse
DOSE/DURATION :
900 mg/kg
TOXIC EFFECTS :
Details of toxic
effects not reported other than lethal dose value
REFERENCE :
ARZNAD
Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960
Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,445,1957
TYPE OF TEST
:
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES
OBSERVED :
Rodent - mouse
DOSE/DURATION :
71 mg/kg
TOXIC EFFECTS :
Details of
toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD
Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960
Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,445,1957
TYPE OF TEST
:
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES
OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS
:
Details of toxic effects not reported other than lethal dose value
REFERENCE
:
VLUBB6 Vestnik Leningradskogo Universiteta, Biologiya. Journal of Leningrad University,
Biology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1956-
Volume(issue)/page/year: (3),97,1984 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST
:
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED
:
Rodent - rat
DOSE/DURATION :
2730 mg/kg/13W-I
TOXIC EFFECTS :
Endocrine -
changes in spleen weight
REFERENCE :
GISAAA Gigiena i Sanitariya. For English
translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 38(9),19,1973 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988
PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S.
Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA
*** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey
(1974) NOHS Hazard Code - 80076 No. of Facilities: 101624 (estimated) No. of Industries: 308
No. of Occupations: 153 No. of Employees: 930493 (estimated) NOES - National Occupational
Exposure Survey (1983) NOES Hazard Code - 80076 No. of Facilities: 49146 (estimated) No. of
Industries: 268 No. of Occupations: 169 No. of Employees: 943961 (estimated) No. of Female
Employees: 347961 (estimated)
FAQ
1.What is Sodium Tripolyphosphate?
2.How is Sodium Tripolyphosphate produced?
3.How is Sodium Tripolyphosphate stored and distributed?
Store under dry inert gas, keep container tightly closed, store in a cool,
dry place
Packed in galvanized iron drums. Store in a cool, ventilated place. The storage should
be dedicated and not mixed with other items. Pay attention to fire prevention.
Polymerization inhibitor should be added before storage and transportation.
Before transportation, check whether the packing container is complete and sealed, and
make sure the container is not leaking, collapsing, falling or damaged during
transportation. Strictly prohibit mixing and transporting with oxidizing agents, acids,
alkalis, edible chemicals and so on. The transport vehicle and ship must be thoroughly
cleaned and sterilized, otherwise it is not allowed to ship other items. When
transported by ship, the fitting position should be far away from bedrooms, kitchens,
and isolated from the cabin, power supply, fire source and other parts. Road
transportation should follow the prescribed route.
4.What is Sodium Tripolyphosphate used for?
