Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
OY4025000
CHEMICAL NAME :
Metaphosphoric
acid, trisodium salt
CAS REGISTRY NUMBER :
7785-84-4
LAST UPDATED
:
199710
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
H3-O9-P3.3Na
MOLECULAR
WEIGHT :
308.91
WISWESSER LINE NOTATION :
NA3 P-O3*3
HEALTH HAZARD DATA
ACUTE
TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE
:
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3650
mg/kg
TOXIC EFFECTS :
Behavioral - excitement Nutritional and Gross Metabolic - weight
loss or decreased weight gain
REFERENCE :
JPETAB Journal of Pharmacology and
Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)
V.1- 1909/10- Volume(issue)/page/year: 108,117,1953
TYPE OF TEST :
LD50 - Lethal dose,
50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent -
mouse
DOSE/DURATION :
10300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not
reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug
Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 7,445,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent
kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent -
mouse
DOSE/DURATION :
5940 mg/kg
TOXIC EFFECTS :
Details of toxic effects not
reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug
Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 7,445,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent
kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent -
mouse
DOSE/DURATION :
1165 mg/kg
TOXIC EFFECTS :
Details of toxic effects not
reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug
Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 7,445,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent
kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent
- rabbit
DOSE/DURATION :
>4640 mg/kg
TOXIC EFFECTS :
Details of toxic effects
not reported other than lethal dose value
REFERENCE :
NTIS** National Technical
Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific &
Technical Information. Volume(issue)/page/year: OTS0571153
TYPE OF TEST :
LDLo -
Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED
:
Rodent - rabbit
DOSE/DURATION :
240 mg/kg
TOXIC EFFECTS :
Details of toxic
effects not reported other than lethal dose value
REFERENCE :
AEPPAE
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin,
Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year:
169,238,1933 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL
EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code
- T1866 No. of Facilities: 101 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of
Employees: 308 (estimated) No. of Female Employees: 260 (estimated)
