Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
AK1500000
CHEMICAL NAME :
Acetic acid,
zinc(II) salt
CAS REGISTRY NUMBER :
557-34-6
LAST UPDATED :
199710
DATA ITEMS
CITED :
13
MOLECULAR FORMULA :
C4-H6-O4.Zn
MOLECULAR WEIGHT
:
183.47
WISWESSER LINE NOTATION :
QV1 &-ZN-
HEALTH HAZARD DATA
ACUTE
TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE
:
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2510 mg/kg
TOXIC
EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF
TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE
:
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
57
mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose
value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE
:
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
5
mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose
value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE
:
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
56
mg/kg/7D-I
TOXIC EFFECTS :
Blood - other changes Nutritional and Gross Metabolic -
changes in metals, not otherwise specified Biochemical - Enzyme inhibition, induction, or
change in blood or tissue levels - other Enzymes
TYPE OF TEST :
TDLo - Lowest
published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
80
mg/kg
SEX/DURATION :
male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive -
Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and
count)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE
:
Intravaginal
DOSE :
10525 ug/kg
SEX/DURATION :
female 1 day(s)
pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. #
females pregnant per # sperm positive females; # females pregnant per # females
mated)
MUTATION DATA
TYPE OF TEST :
Mutation in mammalian somatic cells
TEST
SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
10 mg/L
REFERENCE :
MUREAV
Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands)
V.1- 1964- Volume(issue)/page/year: 223,267,1989 *** NIOSH STANDARDS DEVELOPMENT AND
SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational
Hazard Survey (1974) NOHS Hazard Code - 84428 No. of Facilities: 716 (estimated) No. of
Industries: 19 No. of Occupations: 25 No. of Employees: 9751 (estimated) NOES - National
Occupational Exposure Survey (1983) NOES Hazard Code - 84428 No. of Facilities: 1396
(estimated) No. of Industries: 13 No. of Occupations: 19 No. of Employees: 29875 (estimated)
No. of Female Employees: 12193 (estimated)
