Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
NN1350000
CHEMICAL NAME :
Iodic acid,
potassium salt
CAS REGISTRY NUMBER :
7758-05-6
LAST UPDATED :
199701
DATA
ITEMS CITED :
7
MOLECULAR FORMULA :
I-O3.K
MOLECULAR WEIGHT
:
214.00
WISWESSER LINE NOTATION :
KA I-O3
HEALTH HAZARD DATA
ACUTE TOXICITY
DATA
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE
:
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
531 mg/kg
TOXIC
EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
JPETAB Journal of Pharmacology
and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD
21202) V.1- 1909/10- Volume(issue)/page/year: 120,171,1957
TYPE OF TEST :
LD50 -
Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED
:
Rodent - mouse
DOSE/DURATION :
136 mg/kg
TOXIC EFFECTS :
Behavioral -
convulsions or effect on seizure threshold Behavioral - excitement Lungs, Thorax, or
Respiration - other changes
REFERENCE :
JPETAB Journal of Pharmacology and
Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)
V.1- 1909/10- Volume(issue)/page/year: 120,171,1957
TYPE OF TEST :
LDLo - Lowest
published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal -
dog
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time
(including change in righting reflex) Behavioral - food intake (animal)
REFERENCE
:
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St.,
Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,185,1966 ** OTHER MULTIPLE DOSE
TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF
EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
81
gm/kg/15W-C
TOXIC EFFECTS :
Blood - other hemolysis with or without anemia Blood -
changes in erythrocyte (RBC) count
REFERENCE :
TXAPA9 Toxicology and Applied
Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
Volume(issue)/page/year: 1,87,1959 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 80200 No. of Facilities: 1009 (estimated) No. of Industries: 25 No. of
Occupations: 14 No. of Employees: 5356 (estimated) NOES - National Occupational Exposure
Survey (1983) NOES Hazard Code - 80200 No. of Facilities: 3149 (estimated) No. of
Industries: 47 No. of Occupations: 47 No. of Employees: 193692 (estimated) No. of Female
Employees: 164961 (estimated)
