Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
ON7175000
CHEMICAL NAME :
Malic
acid
CAS REGISTRY NUMBER :
6915-15-7
LAST UPDATED :
199701
DATA ITEMS CITED
:
9
MOLECULAR FORMULA :
C4-H6-O5
MOLECULAR WEIGHT :
134.10
WISWESSER LINE
NOTATION :
QVYQ1VQ -L
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST
:
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES
OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie;
Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
Volume(issue)/page/year: -,657,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF
EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent -
rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold,
J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,657,1986 ** ACUTE
TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF
EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION
:
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal
dose value
REFERENCE :
38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev.
ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol.
3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year:
2C,4937,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE
:
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1600 mg/kg
TOXIC
EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE
:
KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650)
Volume(issue)/page/year: #82-0458
TYPE OF TEST :
LD50 - Lethal dose, 50 percent
kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent -
mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not
reported other than lethal dose value
REFERENCE :
38MKAJ "Patty's Industrial Hygiene
and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley &
Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985.
Volume(issue)/page/year: 2C,4937,1982 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988
PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S.
Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA
*** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey
(1974) NOHS Hazard Code - M1766 No. of Facilities: 1278 (estimated) No. of Industries: 11
No. of Occupations: 21 No. of Employees: 8629 (estimated) NOES - National Occupational
Exposure Survey (1983) NOES Hazard Code - M1766 No. of Facilities: 3524 (estimated) No. of
Industries: 44 No. of Occupations: 46 No. of Employees: 80674 (estimated) No. of Female
Employees: 51609 (estimated)
