Common Name	Maltol
CAS Number	118-71-8
Molecular Weight	126.110
Density	1.3±0.1 g/cm3
Boiling Point	284.7±40.0 °C at 760 mmHg
Molecular Formula	C6H6O3
Melting Point	160-164 °C(lit.)
MSDS	Chinese USA
Flash Point	127.3±20.8 °C
Symbol	GHS07
Signal Word	Warning

Density	1.3±0.1 g/cm3
Boiling Point	284.7±40.0 °C at 760 mmHg
Melting Point	160-164 °C(lit.)
Molecular Formula	C6H6O3
Molecular Weight	126.110
Flash Point	127.3±20.8 °C
Exact Mass	126.031693
PSA	50.44000
LogP	0.08
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.561
Water Solubility	1.2 g/100 mL (25 ºC)

CHEMICAL IDENTIFICATION
RTECS NUMBER :
UQ1050000
CHEMICAL NAME :
4H-Pyran-4-one, 3-hydroxy-2-methyl-
CAS REGISTRY NUMBER :
118-71-8
BEILSTEIN REFERENCE NO. :
0112169
LAST UPDATED :
199712
DATA ITEMS CITED :
17
MOLECULAR FORMULA :
C6-H6-O3
MOLECULAR WEIGHT :
126.12
WISWESSER LINE NOTATION :
T6O DVJ B1 CQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1410 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
550 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD16 - Lethal Dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
820 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1620 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1410 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
3720 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
90 gm/kg/90D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
20500 mg/kg/41D-I
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
MUTATION DATA
TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,487,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2610 No. of Facilities: 508 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 1733 (estimated) No. of Female Employees: 642 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R22;R36/37/38
Safety Phrases	S37-S37/39-S26-S36-S36/37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	UQ1050000
HS Code	2932999099

N/A

1.What is maltitol?

It is a disaccharide sugar alcohol composed of a molecule of glucose linked with a molecule of sorbitol. There are two types in the market: crystalline powder and syrup. They are obtained by hydrogenating d-maltose or glucose syrup which are made from starch. The sweetness about 75%-90% of sucrose and produces low calories after digestion.

2.What is it made from?

Mainly produced from corn starch. It also can be derived from other starch sources, such as tapioca, potato and wheat.

3.How is it made?

1.Crystalline maltitol: commercially produced by the hydrogenation of d-maltose, which is obtained by enzyme conversion of starch. The manufacturing processes can be divided into two major steps: the first step is to hydrolyze the starch into maltose syrup, and in the second step, maltose syrup is reduced by hydrogenation to maltitol. 2.Maltitol syrup: manufactured by catalytic hydrogenation of high maltose-content glucose syrup.

4.What are the uses?

Maltitol can be used as a functional sweetener in special food for diabetics, anti-caries and low-calories. In addition, the high sweetness than other sugar alcohols (except xylitol), plus the taste characteristics close to sucrose make maltitol can directly replace sucrose in a variety of sugar-free foods. Commonly, it may be found in the following food: Baking products: bread, biscuits, cookies Confectionery: chewing gum, chocolate, gummy bears Dairy products: ice cream, dessert, yogurt Cereals & snacks: cereal bars, breakfast cereals