Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
OD5075000
CHEMICAL NAME :
Lactic acid,
ethyl ester
CAS REGISTRY NUMBER :
97-64-3
BEILSTEIN REFERENCE NO.
:
1209448
LAST UPDATED :
199701
DATA ITEMS CITED :
10
MOLECULAR FORMULA
:
C5-H10-O3
MOLECULAR WEIGHT :
118.15
WISWESSER LINE NOTATION
:
QVY1&O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal
dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent -
rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not
reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical Toxicology.
(Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
Volume(issue)/page/year: 20,677,1982
TYPE OF TEST :
LDLo - Lowest published lethal
dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent -
rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Lungs,
Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - other changes
REFERENCE
:
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1
Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year:
11,150,1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE
:
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2500 mg/kg
TOXIC
EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE
:
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co.,
428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year:
65,89,1939
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE
:
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2500
mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose
value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics.
(Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 65,89,1939
TYPE OF TEST :
LD50 - Lethal dose, 50 percent
kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent -
mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not
reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and
Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)
V.1- 1909/10- Volume(issue)/page/year: 65,89,1939
TYPE OF TEST :
LD50 - Lethal dose,
50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED
:
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic
effects not reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical
Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20-
1982- Volume(issue)/page/year: 20,677,1982
TYPE OF TEST :
LDLo - Lowest published
lethal dose
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - guinea
pig
DOSE/DURATION :
2605 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration -
dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics.
(Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 76,189,1942 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA
*** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey
(1974) NOHS Hazard Code - A1136 No. of Facilities: 41 (estimated) No. of Industries: 2 No.
of Occupations: 8 No. of Employees: 578 (estimated) NOES - National Occupational Exposure
Survey (1983) NOES Hazard Code - A1136 No. of Facilities: 298 (estimated) No. of Industries:
5 No. of Occupations: 23 No. of Employees: 7298 (estimated) No. of Female Employees: 1962
(estimated)
