Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
MI5230000
CHEMICAL NAME
:
1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-
CAS REGISTRY NUMBER
:
458-37-7
BEILSTEIN REFERENCE NO. :
2306965
LAST UPDATED :
199801
DATA
ITEMS CITED :
13
MOLECULAR FORMULA :
C21-H20-O6
MOLECULAR WEIGHT
:
368.41
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal
dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent -
mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not
reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent
kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent -
mouse
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not
reported other than lethal dose value
MUTATION DATA
TYPE OF TEST :
Cytogenetic
analysis
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
20
mg/L
REFERENCE :
GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233
Spring St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year: 27,95,1981 *** NIOSH
STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4425 No. of
Facilities: 145 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 690
(estimated)
