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vanilla
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Basic
Common Name Vanillin
CAS Number 121-33-5
Molecular Weight 152.147
Density 1.2±0.1 g/cm3
Boiling Point 282.6±20.0 °C at 760 mmHg
Molecular Formula C8H8O3
Melting Point 81-83 °C(lit.)
MSDS Chinese USA
Flash Point 117.6±15.3 °C
Symbol GHS07
Signal Word Warning
Physical Chemistry
Density 1.2±0.1 g/cm3
Boiling Point 282.6±20.0 °C at 760 mmHg
Melting Point 81-83 °C(lit.)
Molecular Formula C8H8O3
Molecular Weight 152.147
Flash Point 117.6±15.3 °C
Exact Mass 152.047348
PSA 46.53000
LogP 1.19
Vapour density 5.3 (vs air)
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.588
Storage condition Refrigerator
Stability Stable. May discolour on exposure to light. Moisture-sensitive. Incompatible with strong oxidizing agents, perchloric acid.
Water Solubility 10 g/L (25 ºC)
Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
YW5775000
CHEMICAL NAME :
Vanillin
CAS REGISTRY NUMBER :
121-33-5
BEILSTEIN REFERENCE NO. :
0472792
LAST UPDATED :
199710
DATA ITEMS CITED :
24
MOLECULAR FORMULA :
C8-H8-O3
MOLECULAR WEIGHT :
152.16
WISWESSER LINE NOTATION :
VHR DQ CO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1580 mg/kg
TOXIC EFFECTS :
Behavioral - coma
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>41700 ug/kg/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Liver - jaundice, other or unclassified
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - miosis (pupillary constriction) Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory stimulation
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3925 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - coma
TYPE OF TEST :
LC - Lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>41700 ug/kg/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
475 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
1320 mg/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section Vascular - acute arterial occlusion Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5010 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Gastrointestinal - peritonitis
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1400 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4480 mg/kg/70D-I
TOXIC EFFECTS :
Cardiac - other changes Blood - changes in spleen Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
273 gm/kg/13W-C
TOXIC EFFECTS :
Liver - other changes Kidney, Ureter, Bladder - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
41700 ug/m3/4H/30D-I
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Blood - changes in erythrocyte (RBC) count Blood - changes in leukocyte (WBC) count
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
20 mg/kg
SEX/DURATION :
female 4 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina
MUTATION DATA
TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
750 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 169,129,1986 *** REVIEWS *** TOXICOLOGY REVIEW FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 15,611,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0609 No. of Facilities: 378 (estimated) No. of Industries: 14 No. of Occupations: 28 No. of Employees: 6740 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0609 No. of Facilities: 10912 (estimated) No. of Industries: 89 No. of Occupations: 97 No. of Employees: 177946 (estimated) No. of Female Employees: 69887 (estimated)
Safety
Symbol GHS07
Signal Word Warning
Hazard Statements H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R22
Safety Phrases S24/25-S22
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS YW5775000
HS Code 2912410000
Preparation

N/A

FAQ

1.What is Vanilla?

Vanilla, spice plant, contains aromatic volatile oils, antioxidants, bactericides, not only can repel flies and mosquitoes, landscaping, air purification, beautification of the living room, but also widely used in cosmetology, bathing, diet and medical treatment. Representative plants are lavender, rosemary, thyme, patchouli and so on. Refers to all herbaceous plants with special aroma and flavor, mostly originated from the Mediterranean coast, divided into annual and perennial 2 kinds. Because vanilla contains alcohol, ketone, ester, ether aromatic compounds, branches and leaves will emit a pleasant aroma, and its roots, stems, leaves, flowers, fruits and seeds can be used by human beings. The branches and leaves of vanilla plants are fragrant all year round, withered but especially survive, is known as the four seasons of fragrance "natural perfume bottle".

2.How is Vanilla produced?

The right place or season to cultivate: before you buy herbs to come back and cultivate them, know where you want to grow them, do you have a patio at home? What are the sunlight conditions? Is the soil texture or well-drained? Do you want to plant in pots or directly on the ground? All these should be clear, and then from these conditions to choose the type of herb to cultivate, even if you do not know the characteristics of the species, you can ask the seller to help choose or give some advice. Some one- or two-year-old species will die after flowering, so it is necessary to carefully choose the right season to plant. Since vanilla is mostly native to high latitudes, it is important to know that under Taiwan's climatic conditions, the cooler climate of winter is more favorable for growth.

3.How is Vanilla stored and distributed?

Store under dry inert gas, keep container tightly closed, store in a cool, dry place Packed in galvanized iron drums. Store in a cool, ventilated place. The storage should be dedicated and not mixed with other items. Pay attention to fire prevention. Polymerization inhibitor should be added before storage and transportation. Before transportation, check whether the packing container is complete and sealed, and make sure the container is not leaking, collapsing, falling or damaged during transportation. Strictly prohibit mixing and transporting with oxidizing agents, acids, alkalis, edible chemicals and so on. The transport vehicle and ship must be thoroughly cleaned and sterilized, otherwise it is not allowed to ship other items. When transported by ship, the fitting position should be far away from bedrooms, kitchens, and isolated from the cabin, power supply, fire source and other parts. Road transportation should follow the prescribed route.

4.What is Vanilla used for?

In Europe and the United States, the use of herbs is like the Chinese kitchen essential onion, ginger, garlic, used to season dishes. Herbs in China also have some traditional methods of consumption, can be used as the main ingredient into the dish, such as arugula, dandelion, tarragon, mint; can also be brewed tea to drink, such as cool refreshing peppermint tea, refreshing and aromatic lemongrass tea and so on. People use aromatic plants as spices, the Warring States period that is used to steam meat, mixed with rice and wine to enhance the flavor; can also be used directly as vegetables and fruits to eat, and as a natural preservative added to the food.

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