Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
OL5540000
CHEMICAL NAME :
Lysine,
L-
CAS REGISTRY NUMBER :
56-87-1
BEILSTEIN REFERENCE NO. :
1722531
LAST
UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA
:
C6-H14-N2-O2
MOLECULAR WEIGHT :
146.22
HEALTH HAZARD DATA
ACUTE TOXICITY
DATA
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE
:
Oral
DOSE :
138 gm/kg
SEX/DURATION :
female 5-15 day(s) after
conception
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted
fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE
:
Oral
DOSE :
72450 mg/kg
SEX/DURATION :
female 10-20 day(s) after
conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality
(e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
TDLo
- Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
90450
mg/kg
SEX/DURATION :
female 10-20 day(s) after conception
TOXIC EFFECTS
:
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted
fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE
:
Oral
DOSE :
81 gm/kg
SEX/DURATION :
female 10-20 day(s) after
conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities -
musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF
EXPOSURE :
Intraperitoneal
DOSE :
44 gm/kg
SEX/DURATION :
female 5-15 day(s)
after conception
TOXIC EFFECTS :
Reproductive - Fertility - other measures of
fertility
MUTATION DATA
TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM
:
Human Lymphocyte
DOSE/DURATION :
10 mg/L
REFERENCE :
MUREAV Mutation
Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
Volume(issue)/page/year: 372,75,1996 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5
mg/m3 JAN 1993