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Basic
Common Name Xylitol
CAS Number 87-99-0
Molecular Weight 152.146
Density 1.5±0.1 g/cm3
Boiling Point 494.5±40.0 °C at 760 mmHg
Molecular Formula C5H12O5
Melting Point 94-97 °C(lit.)
MSDS Chinese USA
Flash Point 261.9±21.9 °C
Physical Chemistry
Density 1.5±0.1 g/cm3
Boiling Point 494.5±40.0 °C at 760 mmHg
Melting Point 94-97 °C(lit.)
Molecular Formula C5H12O5
Molecular Weight 152.146
Flash Point 261.9±21.9 °C
Exact Mass 152.068466
PSA 101.15000
LogP -3.77
Vapour Pressure 0.0±2.9 mmHg at 25°C
Index of Refraction 1.571
Storage condition 2-8°C
Water Solubility SOLUBLE
Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
ZF0800000
CHEMICAL NAME :
Xylitol
CAS REGISTRY NUMBER :
87-99-0
BEILSTEIN REFERENCE NO. :
1720523
LAST UPDATED :
199806
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C5-H12-O5
MOLECULAR WEIGHT :
152.17
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
16500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,297,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>25 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,297,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,297,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,297,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
12500 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Gastrointestinal - ulceration or bleeding from stomach Liver - other changes
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 36(2),25,1971
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
22100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 34,124,1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
18300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,297,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
8500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,352,1995
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
10200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,297,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
25 gm/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Gastrointestinal - ulceration or bleeding from stomach Liver - other changes
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 36(2),25,1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Biochemical - Metabolism (Intermediary) - other
REFERENCE :
FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 31,726,1972 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2606 No. of Facilities: 53 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 984 (estimated) No. of Female Employees: 796 (estimated)
Safety
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS ZF0800000
HS Code 2905491000
Preparation

N/A

FAQ

1.What is Xylitol?

Xylitol is an organic compound, native to Finland, that is a natural sweetener extracted from birch, oak, corn cobs, bagasse and other plant materials. In nature, xylitol is widely distributed, widely found in a variety of fruits, vegetables, cereals, but the content is very low. For the human body, xylitol is not a "foreign product", it is the normal sugar metabolism of the body intermediates. It is white crystal or crystalline powder, odorless, and has moisture attraction. Very soluble in water, slightly soluble in ethanol. Melting point (general rule 0612) is 91.0~94.5°C. Xylitol can be classified as polyols and sugar alcohols

2.How is Xylitol produced?

The process route of this method is as follows: raw material → hydrolysis → neutralization → concentration → decolorization → ion exchange → concentration → hydrogenation → concentration → crystallization → separation → packaging In the purification process of hydrolyzed liquid, one neutralization and one ion exchange process is adopted, and on the basis of this process, one hydrogenation liquid ion exchange is added, which becomes one neutralization and decarburization and two exchange processes, all of which belong to neutralization and decarburization process. We know that in the production process of xylitol, corn cob is first hydrolyzed to produce hydrolysis solution, hydrolysis should be added catalyst - sulfuric acid, and after hydrolysis, sulfuric acid exists in the hydrolysis solution, but in the production process, this part of the sulfuric acid must be removed, as the name implies, the neutralization and deacidification process is the use of neutralization methods to remove the acid, the neutralizing agent usually use The neutralizing agent is usually calcium carbonate. Sulfuric acid is neutralized by calcium carbonate to form gypsum - calcium sulfate, calcium sulfate solubility in water is very small, most of the gypsum will become precipitation removed by filtration.

3.How is Xylitol stored and distributed?

1. Food grade should be transported and stored according to food hygiene requirements. Avoid mixing and transporting, and load and unload lightly when handling to prevent damage to the package. 2. Precautions for safe operation: In places where dust is generated, provide suitable exhaust equipment. General fire protection measures. 3. Storage conditions:Keep sealed and keep away from light Temperature conditions:Room temperature 4. Moisture-proofing:To avoid the bag from breaking, to avoid its moisture and rain, so as to ensure that its properties will not change. To avoid unnecessary losses. 5. Anti-temperature: when under the influence of high temperature, performance, properties will be more or less affected, therefore, in the storage must avoid high temperature. 6. Fire prevention: When storing, pay special attention to fire prevention.

4.What is Xylitol used for?

According to China's "food additives use of health standards" (GB2760-1996) in the regulations: xylitol can be used in place of sugar in accordance with normal production needs for confectionery, pastries, beverages. It is stated on the label that it is suitable for diabetics to consume. In actual production, xylitol can be used as sweetener and wetting agent. The reference dosage for food products is 43% for chocolate, 64% for chewing gum, 40% for jams and jellies, and 50% for flavored ketchup. Xylitol can also be used in condensed milk, toffee, fudge and so on. When used in pastries, it does not produce browning. A small amount of fructose can be added when making pastries that require browning. Xylitol can inhibit the growth and fermentation activity of yeast, so it should not be used in fermented foods.

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