| Common Name | kojic acid |
| CAS Number | 501-30-4 |
| Molecular Weight | 142.11 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 401.7±45.0 °C at 760 mmHg |
| Molecular Formula | C6H6O4 |
| Melting Point | 152-155 °C(lit.) |
| MSDS | Chinese USA |
| Flash Point | 179.9±22.2 °C |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 401.7±45.0 °C at 760 mmHg |
| Melting Point | 152-155 °C(lit.) |
| Molecular Formula | C6H6O4 |
| Molecular Weight | 142.11 |
| Flash Point | 179.9±22.2 °C |
| Exact Mass | 142.026611 |
| PSA | 70.67000 |
| LogP | -0.64 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.607 |
| Storage condition | Refrigerator |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| Water Solubility | SOLUBLE |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | Xn |
| Risk Phrases | R40 |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | UQ0875000 |
| HS Code | 29329995 |
N/A
1.What is Kojic Acid?
Tretinoin crystals are prismatic, acicular and colorless. Tretinoin is soluble in water, alcohol, acetone, slightly soluble in ether, ethyl acetate, chloroform, pyridine, insoluble in most other solvents. It can be purified by crystallization in solvents such as acetone, ethyl acetate, etc. It can also be sublimated at 150-200°C under reduced pressure. The melting point reported in the literature is 151 to 154°C. Tretinoin and its 5,7-diethyl ester derivatives have specific absorption peaks at 315 nm and 255 nm, respectively. Tretinoin is unstable to light and heat Chemicalbook determined that the concentration of 0.5% of the solution of tretinoin at different pH 100 ℃ treatment for 3h or sunlight irradiation for 5h, the result is that in the range of pH5 ~ 7 solution becomes yellowish ~ yellowish-brown, while in the pH4 there is little change. Tretinoin has a special red color with ferric chloride, which can be used to quantify tretinoin. Tretinoin can reduce Ferrin's reagent and silver ammonia nitrate, and there is an alcohol hydroxyl group near the carbonyl group in its molecular structure, which can generate salts with many metals, and other hydroxyl groups can generate ether and ester derivatives.
2.How is Kojic Acid produced?
1. Industry commonly used starch or molasses as raw materials for fermentation, refining and obtained. The microorganisms that can produce acetic acid are Aspergillus genus (including Aspergillus oryzae, Aspergillus flavus, Aspergillus albicans, Aspergillus fischeri, Aspergillus grey-green, Aspergillus leucocephalus, etc.). 2. oblique strain seed culture fermentation tank culture ↓ medium filtration 3. filtrate concentration under reduced pressure → crystallization and recrystallization of dry Aspergillus acid finished products. 4. It is produced by a variety of Aspergillus species and Aspergillus oryzae metabolism.
3.How is Kojic Acid stored and distributed?
Store under dry inert gas, keep container tightly closed, store in a cool, dry place Store in a cool, ventilated place. The storage should be dedicated and not mixed with other items. Pay attention to fire prevention. Polymerization inhibitor should be added before storage and transportation. Before transportation, check whether the packing container is complete and sealed, and make sure the container is not leaking, collapsing, falling or damaged during transportation. Strictly prohibit mixing and transporting with oxidizing agents, acids, alkalis, edible chemicals and so on. The transport vehicle and ship must be thoroughly cleaned and sterilized, otherwise it is not allowed to ship other items. When transported by ship, the fitting position should be far away from bedrooms, kitchens, and isolated from the cabin, power supply, fire source and other parts. Road transportation should follow the prescribed route.
4.What is Kojic Acid used for?
(1) As a food preservative, preservative and color protection agent, Kojic Acid can be used as an alternative to chemical preservatives for the processing and color protection of meat food, preservation of fruits and vegetables, and sterilization and anticorrosion of raw food, and it can be used as a preservative to extend the preservation of fresh flowers and their shelf-life. Food add tartaric acid, will not affect its own flavor, aroma and texture, but also can hinder the conversion of nitrite into carcinogenic hazards to the human body nitrosamines, this obstruction or inhibition of cured meat products products have a very important significance of the upgrading of the replacement. (2)As the raw material of food flavor enhancer maltol and ethyl maltol. (3)Tricarboxylic acid can be used as raw material for the production of cephalosporin antibiotics. (4) Kojic acid can be used for flavoring and manufacturing larch cortex and ethyl larch cortex raw materials.
