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sodium citrate
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Basic
Common Name Sodium citrate
CAS Number 68-04-2
Molecular Weight 258.069
Density 1.008 g/mL at 20 °C
Boiling Point N/A
Molecular Formula C6H5Na3O7
Melting Point 300°C
MSDS Chinese USA
Flash Point N/A
Physical Chemistry
Density 1.008 g/mL at 20 °C
Melting Point 300°C
Molecular Formula C6H5Na3O7
Molecular Weight 258.069
Exact Mass 257.972839
PSA 140.62000
Storage condition 2-8°C
Toxicity
CHEMICAL IDENTIFICATION
RTECS NUMBER :
GE8300000
CHEMICAL NAME :
Citric acid, trisodium salt
CAS REGISTRY NUMBER :
68-04-2
LAST UPDATED :
199710
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C6-H5-O7.3Na
MOLECULAR WEIGHT :
258.08
WISWESSER LINE NOTATION :
QV1XQVQ1VQ &-NA- 3
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1548 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,65,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1364 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,65,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
170 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,65,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
449 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,65,1948 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 68905 No. of Facilities: 38675 (estimated) No. of Industries: 165 No. of Occupations: 97 No. of Employees: 200416 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - E0257 No. of Facilities: 403 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 4029 (estimated) No. of Female Employees: 2015 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 68905 No. of Facilities: 13473 (estimated) No. of Industries: 96 No. of Occupations: 105 No. of Employees: 301805 (estimated) No. of Female Employees: 163142 (estimated)
Safety
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi,C
Risk Phrases R22:Harmful if swallowed. R40:Limited evidence of a carcinogenic effect. R48/20/22:Harmful: danger of serious damage to health by prolonged exposure through inhalation and if swallowed .
Safety Phrases S36-S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS GE8300000
HS Code 2918150000
Preparation

N/A

FAQ

1.What is Sodium Citrate?

Sodium citrate is an organic compound, soluble in water and glycerol, insoluble in ethanol, aqueous solution is slightly alkaline, commonly used as buffer, complexing agent, bacterial culture medium, used in medicine for diuretic, expectorant, sweating, preventing blood coagulation, and used in food, beverages, electroplating, photography and other aspects. Since the raw materials for the preparation of sodium citrate basically come from food, it is absolutely safe and reliable, and will not be harmful to human health. The Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO) do not impose any limit on the daily intake of sodium citrate, which can be regarded as a non-toxic substance.

2.How is Sodium Citrate produced?

Calcium Citrate + Soda Ash Method In this method, calcium citrate is mixed with soda ash in a complex decomposition reaction, and the insoluble matter is filtered out to obtain sodium citrate. The product purity is poor and the operation process is long. Some years ago, it was reported that by adjusting the pH value of the mixing conditions, the process was simplified, the production cost was reduced, and better quality products were obtained. Resin exchange method has been used to produce sodium citrate. The fermentation broth through the ionic resin exchange, and then use sodium hydroxide solution to elute the adsorption of citric acid, the resulting sodium salt solution by the concentration of crystallization and other products to obtain sodium citrate. This method is pollution-free and low cost.

3.How is Sodium Citrate stored and distributed?

1. Food grade should be transported and stored according to food hygiene requirements. Avoid mixing and transporting, and load and unload lightly when handling to prevent damage to the package. 2. Precautions for safe operation: In places where dust is generated, provide suitable exhaust equipment. General fire protection measures. 3. Storage conditions:Keep sealed and keep away from light Temperature conditions:Room temperature 4. Moisture-proofing:To avoid the bag from breaking, to avoid its moisture and rain, so as to ensure that its properties will not change. To avoid unnecessary losses. 5. Anti-temperature: when under the influence of high temperature, performance, properties will be more or less affected, therefore, in the storage must avoid high temperature. 6. Fire prevention: When storing, pay special attention to fire prevention.

4.What is Sodium Citrate used for?

Sodium citrate has a wide range of uses due to its excellent properties. Sodium citrate is non-toxic, has pH-adjusting properties and good stability, so it can be used in the food industry. Sodium citrate is used as food additives with the greatest demand, mainly used as flavoring agent, buffering agent, emulsifier, swelling agent, stabilizer, etc. In addition, sodium citrate is paired with citric acid, which is used as gelling agent, nutritional supplement and flavor agent for various jams, jellies, fruit juices, beverages, cold drinks, dairy products and pastries. Food safety is attracting more and more attention, in order to remove pesticide residues have been developed containing sodium citrate special cleaning vegetables and fruits cleaning agent.

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